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Drug-Induced Fanconi Syndrome in a Patient with Breast Cancer: A Case Report
https://doi.org/10.14994/tohojmed.2018-006
https://doi.org/10.14994/tohojmed.2018-00627444b12-c244-45c9-be10-f643968c3df0
| 名前 / ファイル | ライセンス | アクション |
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td38349968.pdf (145.1 KB)
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| Item type | *学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||
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| 公開日 | 2019-02-08 | |||||||||||||||||||||
| タイトル | ||||||||||||||||||||||
| タイトル | Drug-Induced Fanconi Syndrome in a Patient with Breast Cancer: A Case Report(en) | |||||||||||||||||||||
| 言語 | ||||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||||
| キーワード | ||||||||||||||||||||||
| 主題 | fanconi syndrome, zoledronate, breast cancer | |||||||||||||||||||||
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| 資源タイプ | journal article | |||||||||||||||||||||
| ID登録 | ||||||||||||||||||||||
| ID登録 | 10.14994/tohojmed.2018-006 | |||||||||||||||||||||
| ID登録タイプ | JaLC | |||||||||||||||||||||
| 著者 |
Fumi, Saito
× Fumi, Saito
× Tadatoshi, Osaku
× Genki, Sato
× Makoto, Sumazaki
× Yosuke, Sasaki
× Sho, Kijima
× Yoshihisa, Urita
× Hideaki, Ogata
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| 内容記述 | ||||||||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||||||||
| 内容記述 | CASE REPORT | |||||||||||||||||||||
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| 内容記述タイプ | Other | |||||||||||||||||||||
| 内容記述 | Fanconi syndrome (FS) is a rare disease characterized by a dysfunction of the proximal renal tubules. Drug-induced FS may be neglected or misdiagnosed, and most reported cases have occurred due to alkylating agents and platinum compounds. We encountered drug-induced FS in a patient with breast cancer using zoledronate. A 58-year-old woman underwent mastectomy for breast cancer at age 54. Two years later, bone metastases were detected and treated using a combination therapy of anastrozole and zoledronate. After 17 months, everolimus, exemestane, and zoledronate were prescribed. Then, she experienced hypocalcemia and proximal renal tubular dysfunction. FS induced by zoledronate was diagnosed, and zoledronate was immediately discontinued. This resulted in immediate and sustained improvement in renal function. In the past, three cases of zoledronate-induced FS were reported. All patients were prescribed zoledronate in combination with molecularly targeted drugs. Close monitoring of proximal tubular function is recommended for such patients. | |||||||||||||||||||||
| 書誌情報 |
ja : Toho Journal of Medicine en : Toho Journal of Medicine 巻 4, 号 4, p. 146-151, 発行日 2018-12-01 |
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| 出版者 | ||||||||||||||||||||||
| 出版者 | The Medical Society of Toho University | |||||||||||||||||||||
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| 収録物識別子タイプ | PISSN | |||||||||||||||||||||
| 収録物識別子 | 21891990 | |||||||||||||||||||||
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| 出版タイプ | VoR | |||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||
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| 内容記述 | TD38349968 | |||||||||||||||||||||
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| 内容記述タイプ | Other | |||||||||||||||||||||
| 内容記述 | TOHO University Scholarly Publication | |||||||||||||||||||||
| 出版地 | ||||||||||||||||||||||
| 内容記述 | Tokyo | |||||||||||||||||||||
