{"created":"2024-10-08T11:07:12.281555+00:00","id":2002873,"links":{},"metadata":{"_buckets":{"deposit":"9e3f383f-abf4-45cc-af24-215c6baf38ba"},"_deposit":{"created_by":82,"id":"2002873","owner":"82","owners":[82],"pid":{"revision_id":0,"type":"depid","value":"2002873"},"status":"published"},"_oai":{"id":"oai:toho.repo.nii.ac.jp:02002873","sets":["1726902243533:1727660391178:1727660708223"]},"author_link":[],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-12-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"151","bibliographicPageStart":"146","bibliographicVolumeNumber":"4","bibliographic_titles":[{"bibliographic_title":"Toho Journal of Medicine","bibliographic_titleLang":"ja"},{"bibliographic_title":"Toho Journal of Medicine","bibliographic_titleLang":"en"}]}]},"item_10001_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"CASE REPORT","subitem_description_language":"en","subitem_description_type":"Other"},{"subitem_description":"Fanconi syndrome (FS) is a rare disease characterized by a dysfunction of the proximal renal tubules. Drug-induced FS may be neglected or misdiagnosed, and most reported cases have occurred due to alkylating agents and platinum compounds. We encountered drug-induced FS in a patient with breast cancer using zoledronate. A 58-year-old woman underwent mastectomy for breast cancer at age 54. Two years later, bone metastases were detected and treated using a combination therapy of anastrozole and zoledronate. After 17 months, everolimus, exemestane, and zoledronate were prescribed. Then, she experienced hypocalcemia and proximal renal tubular dysfunction. FS induced by zoledronate was diagnosed, and zoledronate was immediately discontinued. This resulted in immediate and sustained improvement in renal function. In the past, three cases of zoledronate-induced FS were reported. All patients were prescribed zoledronate in combination with molecularly targeted drugs. Close monitoring of proximal tubular function is recommended for such patients.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10001_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.14994/tohojmed.2018-006","subitem_identifier_reg_type":"JaLC"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Medical Society of Toho University","subitem_publisher_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"21891990","subitem_source_identifier_type":"PISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1726887171532":{"attribute_name":"レコードID","attribute_value_mlt":[{"subitem_description":"TD38349968","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_1726887212651":{"attribute_name":"資源タイプ(ローカル)","attribute_value_mlt":[{"subitem_description":"TOHO University Scholarly Publication","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_1726887247123":{"attribute_name":"出版地","attribute_value_mlt":[{"subitem_description":"Tokyo","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Division of Breast and Endocrine Surgery, Department of Surgery, Toho University School of Medicine","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Fumi, Saito","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Division of Breast and Endocrine Surgery, Department of Surgery, Toho University School of Medicine","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Tadatoshi, Osaku","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Division of Diabetes, Metabolism and Endocrinology, Department of Medicine, Toho University School of Medicine","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Genki, Sato","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Division of Breast and Endocrine Surgery, Department of Surgery, Toho University School of Medicine","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Makoto, Sumazaki","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Department of General Medicine and Emergency Care, Toho University School of Medicine","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Yosuke, Sasaki","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Department of General Medicine and Emergency Care, Toho University School of Medicine","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Sho, Kijima","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Department of General Medicine and Emergency Care, Toho University School of Medicine","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Yoshihisa, Urita","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Division of Breast and Endocrine Surgery, Department of Surgery, Toho University School of Medicine","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Hideaki, Ogata","creatorNameLang":"en"}],"creatorType":"Author"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","displaytype":"detail","filename":"td38349968.pdf","filesize":[{"value":"145.1 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://toho.repo.nii.ac.jp/record/2002873/files/td38349968.pdf"},"version_id":"34809620-a673-42ac-8628-7f04f1d11776"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"fanconi syndrome","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"zoledronate","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"breast cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Drug-Induced Fanconi Syndrome in a Patient with Breast Cancer: A Case Report","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Drug-Induced Fanconi Syndrome in a Patient with Breast Cancer: A Case Report","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"82","path":["1727660708223"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-02-08"},"publish_date":"2019-02-08","publish_status":"0","recid":"2002873","relation_version_is_last":true,"title":["Drug-Induced Fanconi Syndrome in a Patient with Breast Cancer: A Case Report"],"weko_creator_id":"82","weko_shared_id":-1},"updated":"2024-12-06T08:13:07.322718+00:00"}