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Study on the Effects of Fertility Preservation on the Timing of Breast Cancer Treatment and Oncological Outcomes
https://doi.org/10.14994/tohojmed.2022-019
https://doi.org/10.14994/tohojmed.2022-0194310bdd1-2352-4fef-a60e-18a132112ce2
| 名前 / ファイル | ライセンス | アクション |
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td06064078.pdf (213.2 KB)
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| Item type | *学術雑誌論文 / Journal Article(1) | |||||||||||
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| 公開日 | 2023-03-01 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Study on the Effects of Fertility Preservation on the Timing of Breast Cancer Treatment and Oncological Outcomes(en) | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| キーワード | ||||||||||||
| 主題 | fertility preservation, adolescent and young adult, breast cancer, chemotherapy, amenorrhea | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ | journal article | |||||||||||
| ID登録 | ||||||||||||
| ID登録 | 10.14994/tohojmed.2022-019 | |||||||||||
| ID登録タイプ | JaLC | |||||||||||
| 著者 |
Saito, Fumi
× Saito, Fumi
× Sumazaki, Makoto
× Ogata, Hideaki
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| 内容記述 | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | Original Article | |||||||||||
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| 内容記述タイプ | Other | |||||||||||
| 内容記述 | Background: Breast cancer is the most common cancer among women of reproductive age. Although chemotherapy and endocrine therapy have improved the prognosis, they can induce chemotherapy-related amenorrhoea. Some guidelines recommend fertility preservation before breast cancer treatment. This study aimed to assess whether fertility preservation affects the timing of breast cancer treatment and oncological outcomes. Methods: We performed a retrospective study of 249 patients under 45 years of age diagnosed with breast cancer between 2010 and 2021 at our institution. We compared the interval from breast cancer diagnosis to the start of breast cancer treatment and the prognosis among patients who did and did not undergo fertility preservation. Results: Twenty-two patients (8.8%) underwent fertility preservation (FP group) and 227 (91.2%) did not undergo fertility preservation (non-FP group). The intervals from breast cancer diagnosis to initial treatment were 41.1 days in the FP group and 45.2 days in the non-FP group (p = 0.87). Cancer recurrence was noted in 5 patients in the FP group and in 22 in the non-FP group. Two patients in the FP group and eight in the non-FP group died. There were no differences in relapse-free or overall survival between the two groups (p = 0.07/0.19). Conclusions: There were no differences in the interval from cancer diagnosis to the start of treatment or the oncological outcomes based on whether patients underwent fertility preservation. Fertility preservation should be considered before breast cancer treatment in young cancer patients. | |||||||||||
| 書誌情報 |
ja : Toho Journal of Medicine en : Toho Journal of Medicine 巻 9, 号 1, p. 11-19, 発行日 2023-03-01 |
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| 出版者 | ||||||||||||
| 出版者 | The Medical Society of Toho University | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||
| 収録物識別子 | 21891990 | |||||||||||
| 著者版フラグ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
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| 内容記述 | TD06064078 | |||||||||||
| 資源タイプ(ローカル) | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | TOHO University Scholarly Publication | |||||||||||
| 出版地 | ||||||||||||
| 内容記述 | Tokyo | |||||||||||
