| Item type |
*学術雑誌論文 / Journal Article(1) |
| 公開日 |
2021-09-10 |
| タイトル |
|
|
タイトル |
Evaluation of Psychosomatic Stress in Elective Spine Surgery by Measurement of Salivary Chromogranin A(en) |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
perioperative stress, mental stress, spine surgery, chromogranin A, minimally invasive surgery |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| ID登録 |
|
|
ID登録 |
10.14994/tohojmed.2020-029 |
|
ID登録タイプ |
JaLC |
| 著者 |
Hasegawa, Keiji
| en |
Hasegawa, Keiji
Department of Orthopedic Surgery, Faculty of Medicine, Toho University Omori Medical Center
|
Search repository
Wada, Akihito
| en |
Wada, Akihito
Department of Orthopedic Surgery, Faculty of Medicine, Toho University Omori Medical Center
|
Search repository
Fukutake, Katsunori
| en |
Fukutake, Katsunori
Department of Orthopedic Surgery, Faculty of Medicine, Toho University Omori Medical Center
|
Search repository
Nakamura, Kazumasa
| en |
Nakamura, Kazumasa
Department of Orthopedic Surgery, Faculty of Medicine, Toho University Omori Medical Center
|
Search repository
Nishiwaki, Yuji
| en |
Nishiwaki, Yuji
Department of Environmental and Occupational Health, Faculty of Medicine, Toho University Omori Medical Center
|
Search repository
Takahashi, Hiroshi
| en |
Takahashi, Hiroshi
Department of Orthopedic Surgery, Faculty of Medicine, Toho University Omori Medical Center
|
Search repository
|
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Original Article |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Introduction: Physical stress, such as operative time, blood loss, surgical wound size, and postoperative pain, is considered to be surgical stress. However, anxiety about and fear of surgery are also important elements of mental stress in surgery and are factors that may delay postoperative recovery. We determined changes in six test markers after spinal surgery and examined their associations with mental and physical stress-related items to evaluate the clinical usefulness of those markers. Methods: Salivary chromogranin A (CgA) and five other markers (C-reactive protein (CRP), white blood cells (WBC) and interleukin-6 (IL-6) in serum, and amylase (Amy) and cortisol (Cor) in saliva) were measured in 46 patients before elective spine surgery and on postoperative days 1 and 7. At the same time, mental traits and psychological state were evaluated using mental stress-related items on the State-Trait Anxiety Inventory (STAI), a psychological stress test. Physical stress-related items of visual analog scale for pain, operative time, blood loss, and muscle invasiveness were also evaluated. The relationships of changes in six markers from pre- to post-surgery with the physical and mental stress-related items were examined using univariate and multivariate analyses. Results: Changes in CRP, IL-6, and Cor after surgery were associated with physical stress. There was only a weak association of changes in CgA with mental stress (postoperative anxiety). Conclusions: Measurement of changes in salivary CgA after surgery may be useful for objective evaluation of mental stress in the perioperative period of spinal surgery, and this warrants further study. |
| 書誌情報 |
ja : Toho Journal of Medicine
en : Toho Journal of Medicine
巻 7,
号 3,
p. 108-115,
発行日 2021-09-01
|
| 出版者 |
|
|
出版者 |
The Medical Society of Toho University |
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
21891990 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| レコードID |
|
|
内容記述 |
TD31089285 |
| 資源タイプ(ローカル) |
|
|
内容記述タイプ |
Other |
|
内容記述 |
TOHO University Scholarly Publication |
| 出版地 |
|
|
内容記述 |
Tokyo |
td31089285.pdf (86.1 KB)
