{"created":"2024-10-08T23:55:06.063797+00:00","id":2003186,"links":{},"metadata":{"_buckets":{"deposit":"20e3751b-5f2d-441e-81a6-cc1e9f0dd827"},"_deposit":{"created_by":82,"id":"2003186","owner":"82","owners":[82],"pid":{"revision_id":0,"type":"depid","value":"2003186"},"status":"published"},"_oai":{"id":"oai:toho.repo.nii.ac.jp:02003186","sets":["1725419731898:1727661177946"]},"author_link":[],"item_10001_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Fecal carriage of antibiotic-resistant Enterobacteriaceae in patients following admission screening","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"20","bibliographicPageStart":"13","bibliographicVolumeNumber":"18","bibliographic_titles":[{"bibliographic_title":"東邦看護学会誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Journal of Toho Society for Nursing Research","bibliographic_titleLang":"en"}]}]},"item_10001_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究報告","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"[目的]入院時の患者糞便試料より分離された腸内細菌に対して各種抗菌薬の感受性および遺伝学的性状を調査し、入院時の患者における抗菌薬耐性腸内細菌の保菌状況について明らかにした。[方法]2017年5月～2018年3月に東京都および北海道の地域中核病院において入院時の患者63名を対象に同意を得て糞便を採取後、抗菌薬含有培地にて培養し、検出された腸内細菌に対してClinical and Laboratory Standards Institute(CLSI)の国際標準法を用いてカルバペネム耐性腸内細菌科細菌(Carbapenem-resistant Enterobacteriaceae: CRE)およびExtended-spectrum β-lactamases(ESBLs)産生菌の同定を行い、耐性因子の解析を行った。なお、入院時の患者とは、入院から48時間以内の患者とした。[結果]対象とした63 例よりカルバペネム系抗菌薬耐性腸内細菌が2例、第3世代セフェム耐性の腸内細菌が6例より検出され、そのうちCREおよびESBLs産生株はそれぞれ1株および4株検出された。CREはカルバペネマーゼ非産生性かつIMP, VIM遺伝子の主要な関連遺伝子の保有は認められず、耐性因子の特定はできなかった。ESBLs産生株4株は日本の医療機関の院内感染の原因菌として主要なタイプであるCTX-M型に分類された。[結論]入院時患者において、カルバペネム系抗菌薬耐性菌が3.2%(CREは1.6%)、第三世代セフェム耐性菌が9.5%(ESBLs産生菌は6.3%)の割合で認められ、市中に各種抗菌薬耐性株を保有する患者が存在することが明らかとなった。このことは入院を契機に耐性菌が医療機関へ持ち込まれる可能性があるため、患者と接触する機会の多い看護職は、この実態を認識するとともに、標準予防策の徹底および必要に応じて接触感染対策を行い、感染制御活動を徹底する必要があると考えられた。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10001_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.14994/tohokango.18.2.13","subitem_identifier_reg_type":"JaLC"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"東邦看護学会","subitem_publisher_language":"ja"},{"subitem_publisher":"トウホウカンゴガッカイ","subitem_publisher_language":"ja-Kana"},{"subitem_publisher":"Toho Society for Nursing Research","subitem_publisher_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"21855757","subitem_source_identifier_type":"PISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1726887171532":{"attribute_name":"レコードID","attribute_value_mlt":[{"subitem_description":"TD16468192","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_1726887212651":{"attribute_name":"資源タイプ(ローカル)","attribute_value_mlt":[{"subitem_description":"TOHO University Scholarly Publication","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_1726887247123":{"attribute_name":"出版地","attribute_value_mlt":[{"subitem_description":"東京","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"東邦大学看護学部感染制御学","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"倉地, 里枝","creatorNameLang":"ja"},{"creatorName":"クラチ, サトエ","creatorNameLang":"ja-Kana"},{"creatorName":"Satoe, KURACHI","creatorNameLang":"en"}],"creatorType":"author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"東邦大学看護学部感染制御学","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"勝瀬(金山), 明子","creatorNameLang":"ja"},{"creatorName":"カツセ(カナヤマ), アキコ","creatorNameLang":"ja-Kana"},{"creatorName":"Akiko, KATSUSE, KANAYAMA","creatorNameLang":"en"}],"creatorType":"author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"東邦大学看護学部感染制御学","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"金坂, 伊須萌","creatorNameLang":"ja"},{"creatorName":"カネサカ, イズモ","creatorNameLang":"ja-Kana"},{"creatorName":"Izumo, KANESAKA","creatorNameLang":"en"}],"creatorType":"author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"中村記念南病院薬剤部","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"山田, 和範","creatorNameLang":"ja"},{"creatorName":"ヤマダ, カズノリ","creatorNameLang":"ja-Kana"},{"creatorName":"Kazunori, YAMADA","creatorNameLang":"en"}],"creatorType":"author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"東京都保健医療公社東部地域病院外科","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"落合, 匠","creatorNameLang":"ja"},{"creatorName":"オチアイ, タクミ","creatorNameLang":"ja-Kana"},{"creatorName":"Takumi, OCHIAI","creatorNameLang":"en"}],"creatorType":"author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"東邦大学看護学部感染制御学","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"小林, 寅喆","creatorNameLang":"ja"},{"creatorName":"コバヤシ, インテツ","creatorNameLang":"ja-Kana"},{"creatorName":"Intetsu, KOBAYASHI","creatorNameLang":"en"}],"creatorType":"author"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","displaytype":"detail","filename":"td16468192.pdf","filesize":[{"value":"836.9 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://toho.repo.nii.ac.jp/record/2003186/files/td16468192.pdf"},"version_id":"3c432631-30eb-4d15-b2f9-9e1af3b51fd8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Carbapenem-resistant Enterobacteriaceae(CRE)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Extended-spectrum β-lactamases(ESBLs)","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"産生菌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"抗菌薬耐性菌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"入院時の患者における抗菌薬耐性腸内細菌の保菌状況","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"入院時の患者における抗菌薬耐性腸内細菌の保菌状況","subitem_title_language":"ja"},{"subitem_title":"ニュウインジ ノ カンジャ ニ オケル コウキンヤク タイセイ チョウナイ サイキン ノ ホキン ジョウキョウ","subitem_title_language":"ja-Kana"},{"subitem_title":"NYUINJI NO KANJA NI OKERU KOKINYAKU TAISEI CHONAI SAIKIN NO HOKIN JOKYO","subitem_title_language":"ja-Latn"}]},"item_type_id":"10001","owner":"82","path":["1727661177946"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-10-06"},"publish_date":"2021-10-06","publish_status":"0","recid":"2003186","relation_version_is_last":true,"title":["入院時の患者における抗菌薬耐性腸内細菌の保菌状況"],"weko_creator_id":"82","weko_shared_id":-1},"updated":"2024-11-26T05:55:12.589239+00:00"}