{"created":"2024-10-08T10:27:17.074844+00:00","id":2002770,"links":{},"metadata":{"_buckets":{"deposit":"2222339c-726d-4538-aa11-72e1981d3011"},"_deposit":{"created_by":82,"id":"2002770","owner":"82","owners":[82],"pid":{"revision_id":0,"type":"depid","value":"2002770"},"status":"published"},"_oai":{"id":"oai:toho.repo.nii.ac.jp:02002770","sets":["1726902243533:1727660390178:1727660575088"]},"author_link":[],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"25","bibliographicPageStart":"22","bibliographicVolumeNumber":"2","bibliographic_titles":[{"bibliographic_title":"Toho Journal of Medicine","bibliographic_titleLang":"ja"},{"bibliographic_title":"Toho Journal of Medicine","bibliographic_titleLang":"en"}]}]},"item_10001_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Case Report","subitem_description_language":"en","subitem_description_type":"Other"},{"subitem_description":"Serum p53 antibody (s-p53-Ab) is the most recently developed biomarker for breast cancer. Only a few studies have evaluated perioperative s-p53-Ab titers in patients with breast cancer. S-p53-Ab titers were monitored for over 4 years, during the perioperative period and after surgery, in a 75-year-old woman with clinical stage IIA (T2N0M0) breast cancer. The results of screening tests were negative for cancer antigen 15-3, carcinoembryonic antigen (CEA), and National Cancer Center-Stomach-439; only s-p53-Ab level (10.1 U/ml) was positive preoperatively. S-p53-Ab titer remained positive (9.1 U/ml) after radical surgery. Pathologic analysis of surgically resected specimens showed a stage IIB tumor (pT2N1M0). Two years postoperatively, CEA level had increased to 5.9 ng/ml. At this time, liver metastases were detected by computed tomography. Neither chemotherapy nor hormone therapy were effective against this recurrence, and the patient died 3 years after surgery. Perioperative s-p53-Ab titer was a useful marker for long-term monitoring of residual cancer cells in a patient with stage IIA breast cancer.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10001_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.14994/tohojmed.2015.017","subitem_identifier_reg_type":"JaLC"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Medical Society of Toho University","subitem_publisher_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"21891990","subitem_source_identifier_type":"PISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1726887171532":{"attribute_name":"レコードID","attribute_value_mlt":[{"subitem_description":"TD88572949","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_1726887212651":{"attribute_name":"資源タイプ(ローカル)","attribute_value_mlt":[{"subitem_description":"TOHO University Scholarly Publication","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_1726887247123":{"attribute_name":"出版地","attribute_value_mlt":[{"subitem_description":"Tokyo","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Division of General and Gastroenterological Surgery (Omori), Department of Surgery, School of Medicine, Faculty of Medicine, Toho University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Yorichika, Kubota","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Division of General and Gastroenterological Surgery (Omori), Department of Surgery, School of Medicine, Faculty of Medicine, Toho University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Hideaki, Shimada","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Division of General and Gastroenterological Surgery (Omori), Department of Surgery, School of Medicine, Faculty of Medicine, Toho University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Shunsuke, Magoshi","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Division of General and Gastroenterological Surgery (Omori), Department of Surgery, School of Medicine, Faculty of Medicine, Toho University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Fumi, Saito","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Division of General and Gastroenterological Surgery (Omori), Department of Surgery, School of Medicine, Faculty of Medicine, Toho University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Tadatoshi, Osaku","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Department of Surgical Pathology (Omori), School of Medicine, Faculty of Medicine, Toho University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Tetsuo Nemoto","creatorNameLang":"en"}],"creatorType":"Author"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Division of General and Gastroenterological Surgery (Omori), Department of Surgery, School of Medicine, Faculty of Medicine, Toho University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Hideaki, Ogata","creatorNameLang":"en"}],"creatorType":"Autho"},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Division of General and Gastroenterological Surgery (Omori), Department of Surgery, School of Medicine, Faculty of Medicine, Toho University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Hironori, Kaneko","creatorNameLang":"en"}],"creatorType":"Autho"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","displaytype":"detail","filename":"TohoJMed002001022.pdf","filesize":[{"value":"235.1 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://toho.repo.nii.ac.jp/record/2002770/files/TohoJMed002001022.pdf"},"version_id":"3e30b919-9961-4f18-b752-73baeab9bce4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"serum p53 antibody (s-p53-Ab)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"breast cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"surgery","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"monitoring","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Serum p53 Antibody is a Useful Biomarker for Long-Term Monitoring of Breast Cancer: Report of a Recurrent Case After Surgery","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Serum p53 Antibody is a Useful Biomarker for Long-Term Monitoring of Breast Cancer: Report of a Recurrent Case After Surgery","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"82","path":["1727660575088"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2016-04-30"},"publish_date":"2016-04-30","publish_status":"0","recid":"2002770","relation_version_is_last":true,"title":["Serum p53 Antibody is a Useful Biomarker for Long-Term Monitoring of Breast Cancer: Report of a Recurrent Case After Surgery"],"weko_creator_id":"82","weko_shared_id":-1},"updated":"2024-11-26T05:00:06.608775+00:00"}